Find a synthesis workflow that makes sense to you
Wavetable, analogue-inspired, FM and modular instruments invite different ways of building a sound. Compare oscillator design, modulation routing and the way a patch is presented. A clear interface can matter as much as a long feature list when you are trying to finish a part.
For a useful comparison, create the same simple bass, pad or lead in a few candidates. Check the official manual for the features you need, then confirm format and platform support before installing.